张鹏飞

职称

英才副教授

所在部门

光电子科学技术系

行政职务

所属课题组

生物医学光子成像

联系电话

E-mail

pfzhang@tju.edu.cn

办公地址

天津大学第17教学楼401室

主讲课程

《压缩感知理论及工程实践》、《科学仪器》

导师类型

硕士/博士生导师

通讯地址

天津市南开区卫津路92号天津大学精仪学院

邮编

300072

个人经历或学术经历

工作经历：

2018年05月-至今，天津大学精密仪器与光电子工程学院，副教授。

2016年01月-2017年01月，圣路易斯华盛顿大学，副研究员。

2012年06月-2015年06月，洛斯阿拉莫斯国家实验室，博士后副研究员。

2009年02月-2011年12月，美国东卡莱罗纳大学，博士后。

学习经历:

2002.09-2008.07 中科院上海光学精密机械研究所，博士，光学。

1998.09-2002.07 西北工业大学，本科，应用物理。

研究方向

1.  光学压缩成像技术；

2.   光谱检测与成像技术；

3.  超声的光学探测技术；

4.    激光操控与单细胞分析技术；

科研项目、成果、专利

科研项目：

1.   “基于时空复用和编码孔径的光片显微成像方法研究”，国家自然基金面上项目（12474297），2025/1-2028/12，主持;

2.       “口岸食品快检产品和智能监控设备系统化适用性评价研究”，国家重点研发计划课题（2019YFC1605501）, 2019/12-2022/12，主持；

3.       “基于THz-Raman协同智能识别策略的胶质瘤多模态同步定位定性关键机理和技术研究”，国家自然基金联合基金重点项目（U22A20353），2023/01-2026/12，子课题负责人；

4.       “表面等离激元微腔与量子体系的耦合及其量子态调控研究”, 国家重大研发计划(2016YFA0301304), 2016/07-2021/06, 参与；

5.       “Fast High-Resolution Deep Photoacoustic Tomography of Action Potentials in Brains”, 美国健康卫生研究院(NIH)项目(1U01NS090579-01), 09/30/2014-07/31/2018, 参与；

6.       “Whole Body Small Animal Photoacoustic-Ultrasonic Computed Tomography”, 美国健康卫生研究院(NIH)项目 (5R01EB016963-02), 05/01/2013-3/31/2018, 参与；

7.       “Time-gated super-resolution imaging”, 洛斯阿拉莫斯国家实验室LDRD项目(20120227ER)，2011/10-2014/10,   参与；

8.       “Bet-hedging in pathogens: Targeting bacterial persistence to combat infectious disease”, 美国防恐怖署(Defense Threat Reduction Agency)项目， 2014/02-2017/02，参与。

论文、专著：

1.       Haisheng Ou, Pengfei   Zhang, Xiaochun Wang, Manman Lin, Yuanpeng Li, and Guiwen Wang, “Gaining insights into the responses of individual yeast cells to ethanol fermentation   using Raman tweezers and chemometrics,”Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 319, 124584 (2024).

2.       Xuan Zhao, Hang Yuan, Pengfei Zhang*, and Feng Gao, “Snapshot volumetric imaging using rainbow-sheet illumination,” APL Photonics, 9, 026101 (2024).

3.       Yakun Wang, Hang   Yuan, Xuan Zhao, Pengfei Zhang*, Guiwen Wang, and Feng Gao,“Compressive Raman imaging by combining scattering-projection interleaving   with context-aware excitation”, Analytical Methods, 16, 583-588   (2024).

4.       Qi Xia, Zhixuan   Huang, Pengfei Zhang, Hanping Bu, Lei Bao, Da Chen, “Nontargeted detection and recognition of adulterants in milk powder using Raman imaging   and neural networks,” Analyst, 148, 412-421 (2023).

5.       Jongbeom Kim, Gyuwon   Kim, Lei Li, Pengfei Zhang, Jin Young Kim, Yeonggeun Kim, Hyung Ham   Kim, Lihong V Wang, Seungchul Lee, Chulhong Kim, “Deep learning acceleration   of multiscale superresolution localization photoacoustic imaging,” Light:   Science & Applications, 11 (1), 131 (2022).

6.       Mengyu Jia, Lequan   Yu, Wenxing Bai, Pengfei Zhang, Limin Zhang, Wei Wang, Feng Gao，“Single pixel imaging via unsupervised deep   compressive sensing with collaborative sparsity in discretized feature space，”Journal of Biophotonics, 15 (7),   e202200045 (2022).

7.       Pengfei Zhang, Yuhan Miao, Yiwen Ma, Pengfei Niu,   Liang Zhang, Limin Zhang, and Feng Gao, “All-optical ultrasonic detector   based on differential interference,” Opt. Lett., 47, 4790-4793 (2022).

8.       Hang Yuan, Pengfei   Zhang*, Feng Gao, and Xianyu Bao, “Combination of scattering-projection   interleaving and random down-sampling for compressive confocal Raman   imaging,” Opt. Express, 30(25), 44657-44664 (2022).

9.       Hang Yuan, Pengfei   Zhang*, and Feng Gao, “Compressive hyperspectral Raman imaging via   randomly interleaved scattering projection”, Optica 8, 1462-1470   (2021).

10.    Zhenzhen Li; Xiujuan   Zhang; Chengui Xiao; Da Chen; Shushi Huang; Pengfei Zhang*; Guiwen   Wang; Combination of multi-focus Raman spectroscopy and compressive sensing   for parallel monitoring of single-cell dynamics, Journal of Innovative   Optical Health Sciences, 14(6): 2150021 (2021).

11.    Naqash Ali, Zhixuan   Huang, Jing Zong, Yiwen Ma, Yabing Xiao, Lei Wang, Pengfei Zhang*, Da   Chen, “Real-time analysis of mineral elements in oat using laser-induced   breakdown spectroscopy”, Journal of Food Safety and Food Quality, 72(4),   131-136 (2021).

12.    Pengfei Zhang*, Guiwen Wang*, Shushi Huang, “Parallel   micro-Raman spectroscopy of multiple cells in a single acquisition using   hierarchical sparsity”, Analyst, 145, 6032-6037 (2020).

13.    Da Chen, Tong Wang, Yiwen   Ma, Guiwen Wang, Qunwei Kong, Pengfei Zhang*, Ruilong Li*, Rapid   characterization of heavy metals in single microplastics by laser induced   breakdown spectroscopy, Science of The Total Environment, 743, 140850   (2020).

14.    Chen, D., Huang, Z.,   Wang, T., Ma, Y., Zhang, Y., Wang, G., Zhang, P.*, “High-throughput   analysis of single particles by micro laser induced breakdown spectroscopy,” Analytica   Chimica Acta, 1095, 14-19 (2020).

15.    Zhang P.*, Wang, G., Zhang, X., Li, Y.-Q*, “Single-acquisition   2-D multifocal Raman spectroscopy using compressive sensing,” Analytical   Chemistry, 92 (1), 1326-1332 (2020).

16.    Zhang P., Huang, Z., Ma, Y., Li, Y., Ali, N., Li,   Q., Chen, D., “On-line detection of radioactive and non-radioactive heavy   metals in tobacco smoke using portable laser-induced breakdown spectroscopy,”   Analyst, 144, 3567-3572 (2019).

17.    Miao, Z., Zhang P.,   Zhang Y., Huang X., Liu J., Wang G., “Single-cell analysis reveals the   effects of glutaraldehyde and formaldehyde on individual Nosema bombycis   spores.”, Analyst, 144 (9), 3136-3143 (2019).

18.    Zhang, P., Li, L., Lin, L., Shi, J., and Wang, L.   V., “In vivo superresolution photoacoustic computed tomography by   localization of single dyed droplets,”. Light: Science & Applications,   8(1), 36 (2019).

19.    Micheva-Viteva, S.   N., Ross, B. N., Gao, J., Adikari, S., Zhang, P., Mourant, J. R.,   & Hong-Geller, E., “Increased mortality in mice following   immunoprophylaxis therapy with high dosage of nicotinamide in Burkholderia   persistent infections,” Infection and immunity, 87(1),   e00592-18 (2019).

20.    Zhang, P. *, Song, G., and Yu, L., "Optical   Trapping of Single Quantum Dots for Cavity Quantum Electrodynamics," Photonics   Research, 6(3): 182-185 (2018).

21.    Rao, L., Feeherry,   F., Ghosh, S., Liao, X., Lin, X., Zhang, P., Li, Y., Doona, C., and   Setlow, P., "Effects of lowering water activity by various humectants on   germination of spores of Bacillus species with different germinants," Food   Microbiology, 72, 112-127 (2018).

22.    Fu, H., Li, S., Wang,   Y., Song, G., Zhang, P., Wang, L., Yu, L., "Independently Tunable   Ultrasharp Double Fano Resonances in Coupled Plasmonic Resonator System,"   IEEE Photonics Journal, 10(1), 4800409 (2018).

23.    Zhang, P., Li, L., Lin, L., Hu, P., Shi, J., He,   Y., Zhu, L., Zhou, Y., and Wang, L.V., "High-resolution deep functional   imaging of the whole mouse brain by photoacoustic computed tomography in   vivo," Journal of Biophotonics, 11(1): e201700024 (2018).

24.    Lin, L.^†, Zhang, P. ^†, Xu, S., Shi, J., Li, L., Yao, J., Wang, L., and Wang, L.V.,   "Hand-held optical-resolution photoacoustic microscopy," Journal   of Biomedical Optics, 22(4), 041002(2017).

25.    Zhang, P., Goodwin, P.M., and Werner, J.H., "Light-sheet   Microscopy by confocal line scanning of dual-Bessel Beams," Journal   of Biomedical Optics, 21 (10), 100502 (2016).

26.    Tao, Z., Zhang, P.,   Qin, Z., Li, Y.Q. and Wang, G., "Poly(3-hydroxybutyrate) anabolism in   Cupriavidus necator cultivated at various carbon-to-nitrogen ratios: insights   from single-cell Raman spectroscopy," Journal of Biomedical Optics,   21(9), 097005-097005 (2016).

27.    Tao, Z., Peng, L., Zhang,   P., Li, Y.Q. and Wang, G., "Probing the Kinetic Anabolism of   Poly-Beta-Hydroxybutyrate in Cupriavidus necator H16 Using Single-Cell Raman   Spectroscopy," Sensors, 16(8), 1257 (2016).

28.    Liang, J., Zhang,   P., Setlow, P., and Li, Y.-Q., "High-precision fitting measurements   of the kinetics of size changes during germination of individual Bacillus   spores," Applied and Environmental Microbiology, 80(15),   4606-4615 (2014).

29.    Zhang, P., Goodwin, P.M., and Werner, J.H.,   "Fast, super resolution imaging via Bessel-beam stimulated emission   depletion microscopy," Optics Express, 22, 12398-12409   (2014).

30.    Zhang, P., Phipps, M.E., Goodwin, P.M., and   Werner, J.H., "Confocal line scanning of a Bessel beam for fast 3D   Imaging," Optics Letters, 39(12), 3682-3685 (2014).

31.    Zhang, P., Goodwin, P.M., and Werner, J.H.,   “Interferometric three-dimensional single molecule localization microscopy   using a single high numerical-aperture objective,” Applied Optics, 53(31),   7415-7421 (2014).

32.    Zhang, P., Liang, J., Yi, X., Setlow, P., and Li,   Y.-Q., "Monitoring of Commitment, Blocking and Continuation of Nutrient   Germination of Individual Bacillus subtilis Spores," Journal of   Bacteriology, 196(13), 2443-2454 (2014).

33.    Setlow, B., Parish,   S., Zhang, P., Li, Y.-Q., Neely, C., and Setlow, P., "Mechanism   of killing of spores of Bacillus anthracis in a high-temperature gas   environment, and analysis of DNA damage generated by various decontamination   treatments of spores of Bacillus anthracis," Journal of Applied   Microbiology, 116, 805-814 (2014).

34.    Ramirez-Peralta A., Zhang   P., Li, Y.-Q., and Setlow, P., "Effects of Sporulation Conditions on   the Germination and Germination Protein Levels of Spores of Bacillus   subtilis," Applied and Environmental Microbiology, 78,   2689-2697 (2012).

35.    Li, Y., Davis, A.,   Korza G., Zhang P., Li, Y.-Q., Setlow, B., Setlow, P., and Hao B.,   "Role of a SpoVA protein in dipicolinic acid uptake into developing   spores of Bacillus subtilis," Journal of Bacteriology, 194(8),   1875-1884 (2012).

36.    Zhang, P., Kong, L., Wang, G., Scotland, M., Ghosh   S., Setlow, B., Setlow, P., and Li, Y.-Q., "Analysis of the slow   germination of multiple individual superdormant B. subtilis spores using   multifocus Raman microspectroscopy and DIC microscopy," Journal of   Applied Microbiology, 112, 526-536 (2012).

37.    Zhang, P., Thomas, S., Li, Y.-Q., and Setlow, P.,   "Effects of Cortex Peptidoglycan Structure and Cortex Hydrolysis on the   Kinetics of Ca²⁺-Dipicolinic Acid Release During Bacillus subtilis   Spore Germination," Journal of Bacteriology, 194, 646-652   (2012).

38.    Kong, L., Zhang P.,   Setlow, P., and Li, Y.-Q., "Multifocus confocal Raman microspectroscopy   for rapid single-particle analysis," Journal of Biomedical Optics,   16, 120503 (2011).

39.    Wang, G., Zhang,   P., Paredes-Sabja, D., Green, C., Setlow, P., Sarker, M.R. and Li, Y.-Q.,   "Analysis of the germination of individual Clostridium perfringens   spores and its heterogeneity," Journal of Applied Microbiology, 111,   1212–1223 (2011).

40.    Sanchez-Salas, J.-L.,   Setlow, B., Zhang, P., Li, Y.-Q., and Setlow, P., "Maturation of   released spores is necessary for acquisition of full spore heat resistance   during Bacillus subtilis sporulation," Applied and Environmental   Microbiology, 77, 6746-6754 (2011).

41.    Ghosh, S.,   Ramirez-Peralta, A., Gaidamakova, E., Zhang, P., Li, Y.-Q., Daly, M.J.   and Setlow, P., "Effects of Mn levels on resistance of Bacillus   megaterium spores to heat, radiation and hydrogen peroxide," Journal   of Applied Microbiology, 111, 663–670 (2011).

42.    Zhang P., Kong, L., Wang, G., Setlow, P., and Li,   Y.-Q., "Monitoring the wet-heat inactivation dynamics of single spores   of Bacillus species by using Raman tweezers, differential interference   contrast microscopy, and nucleic acid dye fluorescence microscopy," Applied   and Environmental Microbiology, 77, 4754-4769 (2011).

43.    Kong, L., Zhang,   P., Yu, J., Setlow, P., and Li, Y.-Q., "Rapid confocal Raman imaging   using a synchro multifoci-scan scheme for dynamic monitoring of single living   cells," Applied Physics Letters, 98, 213703 (2011).

44.    Wang, G., Zhang,   P., Setlow, P., and Li, Y.-Q., "Kinetics of germination of   wet-heat-treated individual spores of Bacillus species, monitored by Raman   spectroscopy and differential interference contrast microscopy," Applied   and Environmental Microbiology, 77, 3368-3379 (2011).

45.    Kong L., Zhang P.,   Wang, G., Yu, J., Setlow, P., and Li, Y.-Q., "Characterization of   bacterial spore germination using phase-contrast and fluorescence microscopy,   Raman spectroscopy and optical tweezers," Nature Protocols, 6,   625–639 (2011).

46.    Zhang, P., Kong, L., Setlow, P., and Li, Y.-Q.,   "Multiple-trap laser tweezers Raman spectroscopy for simultaneous   monitoring of the biological dynamics of multiple individual cells," Optics   Letters, 35, 3321-3323 (2010).

47.    Zhang, P., Garner, W., Yi, X., Yu, J., Li, Y.-Q.,   and Setlow, P., "Factors affecting variability in time between addition   of nutrient germinants and rapid dipicolinic acid release during germination   of spores of Bacillus species," Journal of Bacteriology, 192,   3608-3619 (2010).

48.    Zhang, P., Kong, L., Setlow, P., and Li, Y.-Q.,   "Characterization of wet-heat inactivation of single spores of Bacillus   species by dual-trap Raman spectroscopy and elastic light scattering," Applied   and Environmental Microbiology, 76, 1796–1805 (2010).

49.    Zhang, P., Kong, L., Wang, G., Setlow, P., and Li,   Y.-Q., "Combination of Raman tweezers and quantitative differential   interference contrast microscopy for measurement of dynamics and   heterogeneity during the germination of individual bacterial spores," Journal   of Biomedical Optics, 15, 056010 (2010).

50.    Coleman, W.H., Zhang,   P., Li, Y.-Q., and Setlow, P., "Mechanism of killing of spores of   Bacillus cereus and Bacillus megaterium by wet heat," Letters in   Applied Microbiology, 50, 507-514 (2010).

51.    Kong, L., Zhang,   P., Yu, J., Setlow, P., and Li, Y.-Q., "Monitoring the kinetics of   uptake of a nucleic acid dye during the germination of single spores of   Bacillus species," Analytical Chemistry, 82, 8717–8724   (2010).

52.    Kong, L., Zhang,   P., Setlow, P., and Li, Y.-Q., "Characterization of bacterial spore   germination using integrated phase contrast microscopy, Raman spectroscopy,   and optical tweezers," Analytical Chemistry, 82, 3840–3847   (2010).

53.    Zhang, P., Setlow, P., and Li, Y.-Q., "Characterization   of single heat-activated Bacillus spores using laser tweezers Raman   spectroscopy," Optics Express, 17, 16480-16491 (2009).

54.    Ghosh, S., Zhang,   P., Li, Y.-Q., and Setlow, P., "Superdormant spores of Bacillus   species have elevated wet-heat resistance and temperature requirements for   heat activation", Journal of Bacteriology, 191, 5584-5591   (2009).

55.    Zhang, H., Zhang,   P., Xu, X. Cheng, F., and Wang, Y., "Optimized temperature   measurement with time-of-flight method", Optics Communications, 282,   3278-3281 (2009).

56.    Zhang, P., Zhang, H., Xu, X., and Wang, Y.,   "Cooling induced by parametric resonance in a magnetic quadrupole   trap", Chinese Optics Letters, 6, 87-89 (2008).

57.    Zhang, P., Zhang, H., Xu, X., and Wang, Y.,   "Monte Carlo simulation of cooling induced by parametric   resonance," Chinese Physics Letters, 25, 89-92(2008).

58.    张鹏飞，许忻平，张海潮，周善钰，王育竹，"紫外光诱导原子脱附技术在单腔磁阱装载中的应用, "物理学报, 56   (6), 3205-3211 (2007).

59.    Zhang H., Zhang P.,   Xu X., Han J., and Wang Y., "Trapping of neutral atoms with a   radio-frequency field ", Chinese Physics Letters, 22 (1),   83-86(2005).

奖励、荣誉、学术兼职

担任Advanced Science, Optica, Environmental Science &   Technology，Photonics Research, APL Photonics, Optics   Letters, Optics Express, Journal of Biomedical Optics, Optical Engineering,   Applied Optics以及Review of Scientific Instruments等学术期刊审稿人。